REVEAL Registry™ Background

The REVEAL Registry is one of the largest and most ambitious research efforts ever undertaken to study patients with PAH. As REVEAL grows and long-term data become available, the REVEAL Registry may provide the most current picture of the clinical course of PAH, as well as updated data on outcomes of different treatments for patients diagnosed with different types of PAH.

The REVEAL Registry is designed to build upon the knowledge collected from previous PAH registry studies. Registries like REVEAL are studies intended to collect information on a broad population of patients about the natural history of disease and current treatment patterns in the real world.

This registry is different from a randomized clinical trial in that no specific treatments are required to be prescribed in REVEAL and few controls are placed on the clinical management of patients. REVEAL is not designed to test any one particular hypothesis about PAH treatment, rather it is intended to generate many hypotheses about which treatments work best for certain types of patients with PAH.

Because of this real-world, observational study design, information from the REVEAL Registry is intended to complement the data collected in a wide variety of ongoing and future clinical trials. Ultimately, data from REVEAL may help clinicians to design better, more informed clinical trials and treatments for PAH.